_ _ _ _ _ _ Artur ¯ ¯ _ _ _ _ _ _Góra¯ ¯ ¯



Head of the Tunneling Group

Artur Gora received Ph.D. degree in Chemistry in 2002 from the Jagiellonian University in Poland. In 2004 he was awarded a JSPS fellowship, and from 2004 to 2006 he was working at the National Institute of Advanced Industrial Science and Technology in Japan. From 2010 to 2013, he has been Marie Curie fellow at the Loschmidt Laboratories of the Masaryk University in Brno, Czech Republic. He is a leader of Tunneling Group focused on protein engineering, drug design and software development facilitating molecular dynamic simulations results analysis and interpretation. Since 2016 he is the Deputy Director for Science at Biotechnology Centre, Silesian University of Technology in Poland.




Important publications

T. Magdziarz, K. Mitusińska, M. Bzówka, A. Raczyńska, A. Stańczak, M. Banas, W. Bagrowska, A. Góra, AQUA-DUCT 1.0: structural and functional analysis of macromolecules from an intramolecular voids perspective, Bioinformatics, , btz946, https://doi.org/10.1093/bioinformatics/btz946

K. Subramanian, K. Mitusińska, J. Raedts, F. Almourfi, H.-J. Joosten, S. Hendriks, S. E. Sedelnikova, S. W. M. Kengen, W. R. Hagen, A. Góra, V. A. P. Martins dos Santos, P. J. Baker, J. van der Oost, P. J. Schaap: Distant Non-Obvious Mutations Influence the Activity of a Hyperthermophilic Pyrococcus furiosus Phosphoglucose Isomerase. Biomolecules 2019, 9(6): 212. DOI: https://doi.org/10.3390/biom9060212 ARTICLEOpen Access

K. Mitusińska, T. Magdziarz, M. Bzówka, A. Stańczak, A. Góra: Exploring Solanum Tuberosum Epoxide Hydrolase Internal Architecture by Water Molecules Tracking. Biomolecules 2018, 8(4): 143. DOI: https://doi.org/10.3390/biom8040143 ARTICLEOpen Access

Baaden, M.; Borthakur, M. P.; Casanova, S.; Coalson, R.; Freger, V.; Gonzalez, M.; Góra, A.; Hinds, B.; Hirunpinyopas, W.; Hummer, G.; Kumar, M.; Lynch, C.; Murail, S.; Noy, A.; Sansom, M.; Song, Q.; Vashisth, H.; Vögele, M. The modelling and enhancement of water hydrodynamics: general discussion. Faraday Discuss. 2018, 354–360, doi:10.1039/C8FD90021C. ARTICLE

Baaden, M.; Barboiu, M.; Bill, R. M.; Casanova, S.; Chen, C. L.; Conner, M.; Freger, V.; Gong, B.; Góra, A.; Hinds, B.; Horner, A.; Hummer, G.; Kumar, M.; Lokesh, M.; Mitra, S.; Noy, A.; Pohl, P.; Sadet, A.; Sansom, M.; Törnroth-Horsefield, S.; Vashisth, H. Structure and function of natural proteins for water transport: General discussion. Faraday Discuss. 2018, 209, 83–95, doi:10.1039/C8FD90019A. ARTICLE

A. Płuciennik, M. Stolarczyk, M. Bzówka, A. Raczyńska, T. Magdziarz, A. Góra: BALCONY: an R package for MSA and functional compartments of protein variability analysis. BMC Bioinformatics 2018, 19: 300. DOI:10.1186/s12859-018-2294-z. ARTICLEOpen Access

K. Subramanian, A. Góra, R. Spruijt, K. Mitusińska, M. Suarez-Diez, V. M. dos Santos, P. J. Schaap: Modulating D-amino acid oxidase (DAAO) substrate specificity through facilitated solvent access. PLoS ONE 13(6): e0198990. DOI: 10.1371/journal.pone.0198990 ARTICLEOpen Access

T. Magdziarz, K. Mitusińska, S. Gołdowska, A. Płuciennik, M. Stolarczyk, M .Ługowska and A. Góra; AQUA-DUCT a ligands tracking tool. Bioinformatics (2017) 33 (13): 2045-2046. DOI: 10.1093/bioinformatics/btx125 ARTICLE

J. Brezovsky, P. Babkova, O. Degtjarik, A. Fortova, A. Gora, I. Iermak, P. Rezacova, P. Dvorak, I. Smatanova, Z. Prokop, R. Chaloupkova, and J. Damborsky, ACS Catalysis 2016, 6, 7597-7610 DOI: 10.1021/acscatal.6b02081 ARTICLE

B. Kozlikova, E. Sebestova, V. Sustr, J. Brezovsky, O. Strnad, L. Daniel, D. Bednar, A. Pavelka, M. Manak, M. Bezdeka, P. Benes, M. Kotry, A. Gora, J. Damborsky, and J. Sochor, “CAVER Analyst 1.0: graphic tool for interactive visualization and analysis of tunnels and channels in protein structures,” Bioinforma. Oxf. Engl., vol. 30, no. 18, pp. 2684–2685, Sep. 2014 ARTICLE.

A. Gora, J. Brezovsky, and J. Damborsky, “Gates of Enzymes,” Chem. Rev., vol. 113, no. 8, pp. 5871–5923, 2013. ARTICLEOpen Access

J. Brezovsky, E. Chovancova, A. Gora, A. Pavelka, L. Biedermannova, and J. Damborsky, “Software tools for identification, visualization and analysis of protein tunnels and channels,” Biotechnol. Adv., vol. 31, no. 1, pp. 38–49, Jan. 2013. ARTICLE

E. Chovancova, A. Pavelka, P. Benes, O. Strnad, J. Brezovsky, B. Kozlikova, A. Gora, V. Sustr, M. Klvana, P. Medek, L. Biedermannova, J. Sochor, and J. Damborsky, “CAVER 3.0: A Tool for the Analysis of Transport Pathways in Dynamic Protein Structures,” PLoS Comput Biol, vol. 8, no. 10, p. e1002708, Oct. 2012. ARTICLEOpen Access



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